Tier 2 — strong
Safety and Metabolism of Long-term Administration of NIAGEN (Nicotinamide Riboside Chloride) in a Randomized, Double-Blind, Placebo-controlled Clinical Trial of Healthy Overweight Adults
Scientific reports
2019
9; 1; 9772
Bibliography
- PubMed
- PMID 31278280
- PubMed Central
- PMC6611812
- Funding
- ChromaDex funded the trial.
- Competing interests
- Disclosures include ChromaDex employment, advisory work and licensed intellectual property.
Study snapshot
| Design | Randomized placebo-controlled human trial |
|---|---|
| Model | Human participants |
| Sample | 140 adults; 35 randomized per arm |
| Intervention | NR chloride 100, 300 or 1000 mg/day versus placebo |
| Duration | 8 weeks |
| Endpoints | Blood NAD+ metabolites; adverse events; safety laboratory measures |
What the study showed, in plain terms
Key findings
What this study can and cannot tell us
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