Tier 3 — preclinical
NAD⁺ repletion improves mitochondrial and stem cell function and enhances life span in mice
Science (New York, N.Y.)
2016
352; 6292; 1436-1443
Bibliography
- PubMed
- PMID 27127236
- Funding
- Indexed grant support includes NIA NIH HHS. The complete funding declaration is not specified in the accessible abstract.
- Competing interests
- A complete competing-interest declaration is not specified in the accessible publication information.
Study snapshot
| Design | Preclinical animal study with supporting assays as applicable |
|---|---|
| Model | Mouse models and stem cells |
| Sample | Aged and muscular-dystrophy mice; multiple stem-cell experiments |
| Intervention | NR supplementation |
| Duration | Model-specific treatment and lifespan follow-up |
| Endpoints | Model-specific physiological outcomes; Biochemical or functional measures reported in the study |
What the study showed, in plain terms
Key findings
What this study can and cannot tell us
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