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Bioavailability of Sulforaphane from two broccoli sprout beverages: results of a short-term, cross-over clinical trial in Qidong, China
Cancer Prevention Research
2011
4(3):384-395
Bibliography
- PubMed
- PMID 21372038
- PubMed Central
- PMC3076202
- Funding
- Supported by USPHS grants P01 ES006052 and R01 CA93780, Center grant ES003819, and the Prevent Cancer Foundation.
- Competing interests
- The authors disclosed no potential conflicts of interest.
Study snapshot
| Design | Randomized short-term crossover clinical trial |
|---|---|
| Model | Healthy adults in Qidong, China |
| Sample | 50 participants |
| Intervention | Seven days of a glucoraphanin-rich beverage and seven days of a pre-hydrolyzed sulforaphane-rich beverage, separated by a 5-day washout, after a 5-day run-in. |
| Duration | 24-day protocol including run-in, two 7-day intervention periods and washout |
| Endpoints | Sulforaphane bioavailability; Urinary sulforaphane and metabolite excretion; Interindividual variability; Elimination kinetics; Tolerability |
What the study showed, in plain terms
Key findings
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