Tier 2 — strong
Aqueous LC-MS/MS quantification of α-/β-nicotinamide mononucleotide in dietary supplements using a pentabromophenyl column
Analytica Chimica Acta
2026
1386:345027
Bibliography
- PubMed
- PMID 41545110
- Competing interests
- The authors declared no known competing financial interests or personal relationships that could have appeared to influence the work.
Study snapshot
| Design | Analytical method-development and validation study followed by testing of eight commercial NMN dietary supplements. |
|---|---|
| Model | Eight commercial NMN supplement products; laboratory analytical chemistry rather than a biological or clinical population. |
| Sample | 8 commercial NMN supplements tested after method validation. |
| Intervention | No clinical intervention. Commercial supplements were analyzed using fully aqueous LC-MS/MS capable of baseline separation of α-NMN and β-NMN. |
| Duration | Not applicable — laboratory product analysis. |
| Endpoints | α-NMN and β-NMN separation; Isomer-specific quantification; Linearity; Sensitivity; Precision; Accuracy; Matrix effects; Label and ingredient authenticity |
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