Tier 1 — highest

Effects of beetroot juice on blood pressure in hypertension according to European Society of Hypertension Guidelines: A systematic review and meta-analysis

Rebecca Grönroos, Robert Eggertsen, Susanne Bernhardsson, Marcus Praetorius Björk
Nutrition, Metabolism and Cardiovascular Diseases 2024 34(10):2240–2256

Bibliography

PubMed
PMID 39069465
DOI
10.1016/j.numecd.2024.06.009
Funding
Not yet independently verified in full text
Competing interests
The authors declare no competing interests (PubMed journal statement).

Study snapshot

DesignSystematic review and random-effects meta-analysis of randomized controlled trials
ModelAdults with clinical hypertension
Sample11 trials; 349 patients
InterventionNitrate-rich beetroot juice versus placebo, water, or no intervention
DurationVaried across trials
EndpointsClinic systolic and diastolic blood pressure; 24-hour ambulatory blood pressure

What the study showed, in plain terms

Beetroot juice produced a pooled reduction in clinic systolic blood pressure in people with hypertension, but 24-hour readings and diastolic blood pressure did not show clear benefit.

Key findings

Clinic systolic BP mean difference −5.31 mmHg (95% CI −7.46 to −3.16); no significant pooled effect on clinic diastolic or 24-hour blood pressure.

What this study can and cannot tell us

Low GRADE certainty, moderate-to-high heterogeneity, beetroot JUICE rather than standardized powder. Cannot assume the same effect for Nitralis.

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Absence of an effect of high nitrate intake from beetroot juice on blood pressure in treated hypertensive individuals: a randomized controlled trial
Catherine P Bondonno et al. · American Journal of Clinical Nutrition · 2015
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Increased nitrate intake from beetroot juice over 4 weeks affects nitrate metabolism, but not vascular function or blood pressure in older adults with hypertension
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Dr. Khaled Mahmoud, MBBChCritical Care Medicine, Longevity Science & Editorial Direction