Tier 2 — strong
Dietary nitrate provides sustained blood pressure lowering in hypertensive patients: a randomized, phase 2, double-blind, placebo-controlled study
Hypertension
2015
65(2):320–327
Bibliography
- PubMed
- PMID 25421976
- PubMed Central
- PMC4288952
- Funding
- British Heart Foundation (reported in PubMed abstract).
- Competing interests
- Not yet independently verified in full text
Study snapshot
| Design | Randomized double-blind phase 2 placebo-controlled trial |
|---|---|
| Model | Adults with hypertension including drug-naive and treated subgroups |
| Sample | 68 randomized (34 drug-naive, 34 treated) |
| Intervention | Daily 250 mL nitrate-rich beetroot juice versus nitrate-depleted placebo juice |
| Duration | Four weeks after two-week run-in |
| Endpoints | Clinic blood pressure; 24-hour ambulatory blood pressure; Home blood pressure; Endothelial function; Arterial stiffness |
What the study showed, in plain terms
Key findings
What this study can and cannot tell us
Citation network
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