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Effect of L-Citrulline Supplementation on Blood Pressure: a Systematic Review and Meta-Analysis of Clinical Trials

Mohammad Sadegh Mirenayat, Sajjad Moradi, Hamed Mohammadi, Mohammad Hossein Rouhani
Current Hypertension Reports 2018 20(11):98

Bibliography

PubMed
PMID 30284051
Funding
Not yet independently verified for this record
Competing interests
Not yet independently verified for this record

Study snapshot

DesignSystematic review and meta-analysis
ModelAdults enrolled in five L-citrulline intervention studies
SampleFive clinical interventions
InterventionL-citrulline supplementation versus control
DurationVaried across five included interventions
EndpointsBrachial and aortic blood pressure

What the study showed, in plain terms

No consistently established significant pooled reduction in brachial or aortic blood pressure in this smaller synthesis.

Key findings

No consistently established significant pooled reduction in brachial or aortic blood pressure in this smaller synthesis.

What this study can and cannot tell us

Small number of heterogeneous interventions; consider later partly overlapping 2019 review and contemporary trials before drawing conclusions.

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Editorial review

Reviewed by the Biohack Blueprint research team

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