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Effect of fucoidan supplementation on glycolipid metabolism, systemic inflammation and gut microbiota in prediabetes: A randomized controlled trial
International Journal of Biological Macromolecules
2025
287:138415
Bibliography
- PubMed
- PMID 39645105
- Funding
- Supported by the Bright Moon Seaweed Group Nutrition and Health Research Fund of the Chinese Nutrition Society (CNS-BMSG2020A63) and the China Postdoctoral Science Foundation (2023M733206). Qingdao Bright Moon Seaweed Group provided the fucoidan.
- Competing interests
- The authors declared no conflict of interest.
Study snapshot
| Design | Randomized double-blind placebo-controlled parallel trial |
|---|---|
| Model | Chinese adults with prediabetes |
| Sample | 70 randomized; 55 completed |
| Intervention | Fucoidan 1,000 mg/day versus placebo |
| Duration | 12 weeks |
| Endpoints | Glycated serum protein; Glucose and lipid metabolism; TNF-alpha; IL-6; LPS; Gut microbiome composition |
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