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Resistance training combined with creatine supplementation: a three-level meta-analysis of multidimensional outcomes from strength enhancement to body composition remodeling

Hai Wang, Hao Wang, Xianyang Xin, Zheng Yi
J Int Soc Sports Nutr 2026 23(sup1):2718316

Bibliography

PubMed
PMID 42765482
Funding
Supported by the Science and Technology Strengthening Project of Capital University of Physical Education and Sports (Grant No. 155225002/011).
Competing interests
Authors reported no potential conflict of interest.

Study snapshot

DesignSystematic review and three-level meta-analysis
ModelHuman
Sample63 studies; 1,489 participants
InterventionResistance training plus creatine versus resistance training alone/control
DurationVaried by included trial
EndpointsUpper-body strength; Lower-body strength; Lean mass; Fat mass; Body-fat percentage; Body mass

What the study showed, in plain terms

Large recent meta-analysis integrating multiple correlated outcomes from creatine-plus-resistance-training trials.

Key findings

Creatine added to resistance training improved upper- and lower-body strength and lean mass; fat mass was not significantly changed and body-mass increase was modest.

What this study can and cannot tell us

Nutritional intake and training backgrounds were heterogeneous and incompletely reported; moderator findings were exploratory.

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