Tier 1 — highest
Impact of creatine supplementation alone or combined with exercise on inflammatory and clinical outcomes in chronic musculoskeletal pain treated in the rheumatological field: a systematic review
Nutrition
2026
150:113330
Bibliography
- PubMed
- PMID 42407202
- Funding
- No explicit funding statement was located in the accessible PubMed and publisher abstract records during the 2026-10-02 audit.
- Competing interests
- Authors declared no known competing financial interests or personal relationships that could have influenced the work.
Study snapshot
| Design | Systematic review of randomized and nonrandomized clinical trials |
|---|---|
| Model | Human |
| Sample | 8 studies; 189 participants |
| Intervention | Creatine alone or with exercise versus control/placebo in fibromyalgia, osteoarthritis, rheumatoid arthritis or juvenile idiopathic arthritis |
| Duration | Varied by included study |
| Endpoints | Pain; Physical function; Quality of life; Muscle strength; Skeletal muscle mass; Inflammatory markers |
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