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Plasma nitrate, dietary nitrate, blood pressure, and vascular health biomarkers: a GRADE-Assessed systematic review and dose-response meta-analysis of randomized controlled trials
Nutrition Journal
2025
24(1):47
Bibliography
- PubMed
- PMID 40128734
- PubMed Central
- PMC11931885
- Funding
- Publication funding statement: None. The authors acknowledge support from the Student Research Committee at Iran University of Medical Sciences.
- Competing interests
- Authors declare no competing interests (journal publication).
Study snapshot
| Design | Systematic review and dose-response meta-analysis of 75 randomized controlled trials |
|---|---|
| Model | Human participants in dietary nitrate trials |
| Sample | 75 RCTs; 1,823 participants |
| Intervention | Acute and sustained dietary nitrate supplementation across intervention formats |
| Duration | Acute, short-term, and medium-term protocols across included trials |
| Endpoints | Plasma nitrate and nitrite; Systolic and diastolic blood pressure; Flow-mediated dilation; Pulse-wave velocity; Augmentation index |
What the study showed, in plain terms
Key findings
What this study can and cannot tell us
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