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Does creatine supplementation improve strength and power in physically active individuals on a vegan diet? a randomized, triple-blind, placebo-controlled trial

Miguel López-Moreno, Alejandro Muñoz, Millán Aguilar-Navarro, Jorge Gutiérrez-Hellín, Arturo Franco-Andrés, Pilar López-López, Almudena Crespo-Cañizares, Paula Marrero-Fernández, Scott C Forbes
Eur J Appl Physiol 2026 Online ahead of print

Bibliography

PubMed
PMID 42390589
Funding
Supported by Universidad Francisco de Vitoria (Grant AGL-2024-46).
Competing interests
Miguel López-Moreno reported consulting fees from Danone and Foods For Tomorrow outside the submitted work. Scott C Forbes is a scientific advisor to Bear Balanced and has received creatine donations from Creapure for research. Other authors reported no conflicts.

Study snapshot

DesignRandomized, triple-blind, placebo-controlled trial
ModelHuman
Sample20 physically active vegan adults (10 creatine, 10 placebo; 10 women and 10 men total)
InterventionCreatine monohydrate 0.1 g/kg/day versus placebo while following a normocaloric vegan diet
Duration4 weeks
EndpointsSkeletal muscle mass; Total body water; Body fat; Countermovement jump; Repeated-jump performance; Sprint; Handgrip; Isometric mid-thigh pull; Renal biomarkers

What the study showed, in plain terms

Small 2026 randomized trial directly testing creatine monohydrate in physically active adults following a vegan diet.

Key findings

Creatine increased total body water and some body-composition measures and improved selected lower-body explosive-performance outcomes; sprint and several strength measures did not change significantly.

What this study can and cannot tell us

Only 20 participants and four weeks of follow-up; multiple outcomes increase the risk of chance findings, and results should not be generalized to all vegan adults.

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