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Does creatine cause hair loss? A 12-week randomized controlled trial

Mohammadyasin Lak, Scott C Forbes, Damoon Ashtary-Larky, Sahar Dadkhahfar, Reza Mahmoud Robati, Farshid Nezakati, Makan Khajevandi, Sara Naseri, Arvin Gerafiani, Neda Haghighat, Jose Antonio, Grant M Tinsley
J Int Soc Sports Nutr 2025 22(Suppl 1):2495229

Bibliography

PubMed
PMID 40265319
Funding
Authors reported no funding associated with the work; the paper also acknowledges support from Tose'e Sabz Company, official representative of BPI Sports USA.
Competing interests
Scott C. Forbes disclosed advisory and research-donation relationships; Jose Antonio disclosed ISSN leadership and supplement-brand advisory roles; Grant Tinsley disclosed industry research support and supplement consulting. Other authors declared no conflicts related to the study.

Study snapshot

DesignRandomized controlled trial
ModelHuman
Sample45 resistance-trained men enrolled; 38 completed
InterventionCreatine monohydrate 5 g/day versus maltodextrin placebo
Duration12 weeks
EndpointsDHT; Testosterone; Hair density; Follicular unit count; Hair thickness

What the study showed, in plain terms

First randomized human trial to directly measure hair-follicle health during creatine supplementation.

Key findings

Creatine did not significantly change DHT, DHT:testosterone ratio or measured hair-growth parameters compared with placebo.

What this study can and cannot tell us

Young resistance-trained men only, 12-week duration, and some investigators reported supplement-industry relationships.

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