Tier 2 — strong
Elevation of creatine in resting and exercised muscle of normal subjects by creatine supplementation
Clin Sci (Lond)
1992
83(3):367-374
Bibliography
- PubMed
- PMID 1327657
- Funding
- No explicit funding statement was located in the accessible PubMed or publisher records during Biohack Blueprint's 2026-10-02 audit. This is an audit-status statement, not confirmation that the study received no funding.
- Competing interests
- No explicit competing-interests statement was located in the accessible PubMed or publisher records during Biohack Blueprint's 2026-10-02 audit. This is an audit-status statement, not confirmation that no competing interests existed.
Study snapshot
| Design | Controlled clinical trial |
|---|---|
| Model | Human |
| Sample | 17 muscle-biopsy participants plus acute pharmacokinetic observations |
| Intervention | Creatine monohydrate 5 g repeated multiple times daily |
| Duration | 2 or more days for loading observations |
| Endpoints | Muscle total creatine; Phosphocreatine; Plasma creatine; Urinary creatine |
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Key findings
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