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Meta-Analysis Examining the Importance of Creatine Ingestion Strategies on Lean Tissue Mass and Strength in Older Adults
Nutrients
2021
13(6):1912
Bibliography
- PubMed
- PMID 34199420
- PubMed Central
- PMC8229907
- Funding
- This research received no external funding.
- Competing interests
- Scott Forbes disclosed prior scientific-advisory work for a creatine company. Darren Candow disclosed industry-sponsored creatine research, creatine donations, travel support and AlzChem scientific-advisory-board service. Sergej Ostojic disclosed AlzChem advisory-board service, creatine-related patents and research funding relationships.
Study snapshot
| Design | Systematic review and meta-analysis with dosing-strategy subanalyses |
|---|---|
| Model | Human |
| Sample | Randomized placebo-controlled resistance-training studies in older adults |
| Intervention | Creatine during resistance training, including ≤5 g/day, >5 g/day, loading and training-day-only strategies |
| Duration | Varied; resistance-training interventions |
| Endpoints | Lean tissue mass; Chest-press strength; Leg-press strength; Effects of loading and maintenance strategies |
What the study showed, in plain terms
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- Creatine for Older Adults: Strength, Function, Muscle and Healthy AgingCreatine for older adults: what randomized trials and meta-analyses show about strength, muscle mass, physical function, cognition and practical dosing.Read analysis
- Creatine Loading Phase: How It Works, Dose and Whether You Need ItCreatine loading explained: the classic 20 g/day protocol, how fast it saturates muscle, whether loading is necessary, side effects and lower-dose alternatives.Read analysis
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