How and When to Take Fisetin
Fisetin is fat-soluble, poorly absorbed on an empty stomach, and rapidly metabolised after ingestion. How, when, and with what you take it changes what ends...
Read Article →Fisetin
Fisetin Dosage: Trial-Validated Dose vs Marketing
Every published human trial of fisetin as a senolytic uses 20 mg/kg for two consecutive days, every 28 days. Most commercial capsules recommend 100–500 mg...
Read Article →
Fisetin as a Senolytic: Evidence, Biology, Human Data
Fisetin is the most potent natural senolytic identified in the landmark Mayo Clinic flavonoid screen. Eight years on, the mouse evidence has thickened but no...
Read Article →
Fisetin Benefits: What the Evidence Actually Shows
Fisetin is marketed for senolytic activity, cognitive support, skin, hair, inflammation, and healthy ageing. The preclinical evidence is genuine; the human evidence is mostly pending....
Read Article →
What Is Fisetin? Structure, Sources, and How It Works
Fisetin is a plant flavonoid, most concentrated in strawberries, being studied as a senolytic — a compound that selectively clears senescent cells. Here is the...
Read Article →
Fisetin: A Clinician's Guide to Evidence, Dose & Safety
Fisetin is a plant flavonoid best known as a senolytic — a compound that selectively clears senescent cells in mice. Every published human trial has...
Read Article →
Fisetin Pulse Dosing and the Mayo Clinic Protocol
Every human trial of fisetin as a senolytic uses the same pulse: 20 mg/kg for two consecutive days, then 28 days off. This is the...
Read Article →
Fisetin and Blood Pressure: Does It Raise or Lower It?
Reader questions come from both directions: can fisetin raise blood pressure, and can it lower it? No published human trial has measured either endpoint. Here...
Read Article →
Fisetin Drug Interactions: What to Watch For (2026)
Fisetin is a CYP2C8 substrate and mild inhibitor of several other cytochrome P450 enzymes in vitro. No published human drug-drug interaction study exists. The theoretical...
Read Article →